A Role for Oxidative Phosphorylation In Driving Tricarboxylic acid Cycle Reactions
Most organisms’ aerobic metabolism is controlled by the tricarboxylic acids (TCA) cycles. It’s responsible for the generation ATP and other energy-rich compounds, as well the production of precursors to other metabolic pathways. TCA is made up of eight reactions that are involved in the oxidation and reduction of substrates. Reddy and colleagues (2016) have found that OxPhos is a key component of some TCA cycles’ reactions. This may be because it produces oxidative phosphorylation, rather than an increase in free energy. OxPhos describes the procedure by which electrons can be transferred from a substrate or molecular oxygen to form ATP. The electron transport chain includes a number of redox reaction that allows electron transfers to be made easier. OxPhos participates in TCA’s conversion of succinate and fumarate to succinyl coA. (Fang, et al.2020). These reactions result in electron transfer from succinate to fumarate and?-ketoglutarate into molecular oxygen. This leads to the formation of ATP. The TCA cycle is driven by OxPhos, which suggests that OxPhos may be a key factor. Cont….
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