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What inheritance pattern does sickle cell anemia follow? What are RFLPs and how are they used? If a person has sickle cell anemia and his or her beta globin DNA is cut with Mst II, will the fragments be longer or shorter than those from an individual who is normal? (See figure above) Explain. Inheritance Pattern of Sickle Cell Anemia

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Posted on 
January 2nd, 2023
Home Uncategorized What inheritance pattern does sickle cell anemia follow? What are RFLPs and how are they used? If a person has sickle cell anemia and his or her beta globin DNA is cut with Mst II, will the fragments be longer or shorter than those from an individual who is normal? (See figure above) Explain. Inheritance Pattern of Sickle Cell Anemia

Inheritance Sample of Sickle Cell Anemia

Sickle cell anemia is a hereditary blood dysfunction that impacts tens of millions of individuals all over the world. It’s an autosomal recessive situation, which signifies that it’s inherited in a sample of two copies of a mutated gene, one from every mother or father. If each mother and father carry a replica of the mutated gene, there’s a 25% likelihood that the kid will inherit two copies of the mutated gene and be affected by the dysfunction (Bosch & Fuster, 2020). Sickle cell anemia is attributable to the mutation of a gene that impacts the manufacturing of hemoglobin, which is liable for carrying oxygen within the physique. The mutation ends in the formation of irregular hemoglobin (HbS) which causes purple blood cells to turn into distorted and rupture extra simply (Kaname & Okamura, 2019). This results in a variety of signs, together with fatigue, shortness of breath, frequent infections, and anemia.
An individual with sickle cell anemia can move it on to their kids by offering them with one copy of the mutated gene. As such, the inheritance sample of sickle cell anemia is autosomal recessive. Which means that to ensure that a baby to inherit the dysfunction, each mother and father should carry a replica of the mutated gene (Malik et al., 2020). Whereas there isn’t a remedy for the dysfunction, it’s attainable to handle the signs with correct therapy and life-style modifications. Cont…

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