Phospholipase Az (PLA,) is present in many mammalian tissues and pancreatic juice. It is also present in snake and bee venom. Indicate the site of action of PLA2 on the following lipid: 2 CH3 -O O : CH3 – CH 3 H,C A) 1; B) 2; C) 3; D) 4; E) None of the above are recognized by PLAz. 22. Sphingolipidoses are a class of disorders relating to sphingolipid metabolism (Tay-Sachs disease, Fabry’s dise etc). Which of the statements about sphingolipidoses disorders is correct? The Site of Action of Phospholipase A2 on 2 CH3-O O : CH3-CH 3 H,C-C-O-O

Phospholipase A2’s Site of Action on 2 CH3 O O: CH3CH3 H,C–C-O-O

The enzyme phosphatolipase (PLA2) can be found in many tissues of mammalian mammals, as well as pancreatic juice and bee and snake poison. It’s an essential enzyme for the metabolism of fats. The enzyme is also known to help in hydrolysis of the fatty acid esters in phospholipids within the cell membrane. (Agnihotri and colleagues, 2002). Pla2 is responsible for hydrolyzing an ester bond between the fatty acids and the backbone of glycerol, thereby releasing the fatty (Kumar & Sharma, 2016). Hydrolysis of an ester bond between fatty acid and glycerol backbone is critical for the metabolism of Phospholipids. It is also essential to maintain cell membrane integrity. Phospholipase (A2) is an enzyme essential in the metabolism and synthesis of lipids. This enzyme hydrolyzes the ester link between the fatty and the glycerol backbones of the 2 CH3O O :CH3-CH3 H,C-C.O-O. Cont….

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