In the beginning of fatty acid synthesis, acetyl ACP and malonyl ACP come together and form butyryl ACP in a series of four reactions. These reactions are repeated to add more carbons. What are these four reactions? Draw a simple structure for each step to show the product of this reaction. What coenzyme is required for two of these steps? The Four Reactions of Fatty Acid Synthesis and the Formation of Butyryl ACP

Four Reactions of Fatty Acid Synthesis & the Formation of Butyryl ACP

Fatty acid synthesizing is a sequence of four reactions. It begins with the mixture of malonyl and acetyl ACCP to create butyryl ACP. The four reactions include the enoyl reduce reaction, ketoacyl synthase react, ketoacyl reductase response, ketoacyl reductase and the ACP thioesterase. The first reaction is called the enoyl reduction reaction. It is a combination of acetyl- and malonyl-ACP to produce an acetoacetyl ACCP. The enzyme NADPH -dependent enoyl reduce (NADPH -ER) catalyzes this reaction.
The ketoacyl synthase reacts with malonyl ACCP to add an additional carbon to the acetoacetylACP. The enzyme Acetoacetyl ACP synthase (AAS) catalyzes this reaction.
Third is the ketoacyl reduce reaction. This involves reducing the ketone of Acetoacetyl ACP into an alcohol group. NADPH-dependent Ketoacyl Reductase (NADPHKR) catalyzes this reaction. Cont….

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